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Phenytoin purple glove syndrome

WebNov 10, 2016 · ‘Purple Glove Syndrome’ was so named because of the discoloration of the skin that often accompanies the disorder. This discoloration is accompanied by pain and edema distal to the site of intravenous administration of phenytoin. Purple Glove Syndrome progresses in stages. Webpurple glove syndrome: A condition resulting from IV injection of phenytoin, in which there is discolouration, oedema and blister formation of the hand—or acral parts distal to an IV injection site; the oedema evoked may cause ischaemic necrosis, necessitating amputation

Warfarin and phenytoin drug interaction with possible purple glove syndrome

WebJan 15, 2024 · “Purple Glove syndrome” is a rare side effect that can occur with intravenous administration of phenytoin. It is characterized by worsening distal limb edema and discoloration which can lead to extensive skin necrosis and limb ischemia. WebOct 9, 2024 · Phenytoin may cause purple glove syndrome. Tell your doctor right away if you or your child have skin discoloration, pain, or swelling at the injection site after receiving phenytoin. Phenytoin may affect blood sugar levels. If you or your child notice a change in the results of your blood or urine sugar tests or if you have any questions ... promise rose houston https://myfoodvalley.com

Phenytoin Toxicity - StatPearls - NCBI Bookshelf

WebSep 1, 2024 · Purple glove syndrome (PGS) is an atypical adverse drug reaction that can occur after the administration of intravenous phenytoin. Although definitions of PGS vary, it has been loosely defined as signs and symptoms of progressive edema, discoloration, and pain that occurs following administration of intravenous phenytoin [1]. http://patientsafety.pa.gov/ADVISORIES/Pages/200612_12.aspx WebJan 1, 2024 · Purple Glove Syndrome (PGS) is a rare complication of intravenous phenytoin administration which is illustrated by delayed soft tissue injury of the skin conterminous to the point or distal... labor shortage graph 2021

Purple Glove Syndrome: Recognizing a Rare Complication …

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Phenytoin purple glove syndrome

Purple glove syndrome following intravenous …

WebApr 1, 2016 · Purple glove syndrome is defined as the edema, discoloration, and pain occurring in the distal limb where intravenous phenytoin has been administered. WebPurple glove syndrome following intravenous phenytoin administration N J Prince, C Hill Correspondence to Dr N J Prince, Children's Critical Care Centre, Kings College Hospital, Denmark Hill, London SE5 9RS, UK; …

Phenytoin purple glove syndrome

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WebThe purple-blue discoloration and edema of the right hand and arm. Purple Glove syndrome is a rare complication of intravenous phenytoin infusion. The incidence ranges from 1.7% … WebPurple Glove Syndrome after Phenytoin or Fosphenytoin Administration: Review of Reported Cases and Recommendations for Prevention. Garbovsky LA, Drumheller BC, Perrone J J Med Toxicol 2015 Dec;11(4):445-59. doi: 10.1007/s13181-015-0490-z.

WebSep 1, 2003 · purple glove syndrome children INTRODUCTION Phenytoin has been used in the management of epilepsy for over half a century. Together with intravenous (i.v.) phenobarbitone, i.v. phenytoin remains one of the preferred long-acting anti-convulsant drugs in treating convulsive (tonic–clonic) status epilepticus 1. WebApr 8, 2024 · Purple glove syndrome (PGS) is a rare severe adverse drug reaction typically associated with intravenous (IV) phenytoin administration. PGS is poorly understood and …

WebOct 1, 1998 · Objective: To determine the incidence, risk factors, and long-term sequelae of the purple glove syndrome (PGS) in hospital patients receiving IV phenytoin. Background: … WebPurple glove syndrome (PGS) is a rare complication of intravenous phenytoin use. It typically presents with pain, edema, and discoloration at the injection site that spreads to …

WebJun 28, 2024 · PGS is a rare serious adverse reaction to intravenous phenytoin. Its incidence ranges from 1.5 to 5.9% [ 1 ]. Its manifestation includes pain, skin discolouration, blister formation, sloughing, ulceration, and necrosis.

Webintravenous phenytoin administration is the purple glove syndrome, which is characterized by progressive limb edema, discoloration, and pain. In the only reported systematic study of this syndrome at the time (1998) had the incidence of purple glove syndrome was 5.9% (nine of 152) in patients receiving intravenous phenytoin (1). promise sb thatWebApr 1, 2016 · Though the impact of phenytoin on warfarin has been reported to potentiate the anticoagulant effect or interact in a biphasic manner, the effect of phenytoin on warfarin appears to be... promise rings infinity symbolWebJan 13, 2014 · Phenytoin is the prototypical basic drug that causes a clinical manifestation known as purple glove syndrome (PGS). This syndrome is largely managed through preventive and conservative treatment measures. Promethazine is acidic and can cause a devastating extravasation, particularly if administered inadvertently through the arteriolar … labor shortage georgia