WebNov 10, 2016 · ‘Purple Glove Syndrome’ was so named because of the discoloration of the skin that often accompanies the disorder. This discoloration is accompanied by pain and edema distal to the site of intravenous administration of phenytoin. Purple Glove Syndrome progresses in stages. Webpurple glove syndrome: A condition resulting from IV injection of phenytoin, in which there is discolouration, oedema and blister formation of the hand—or acral parts distal to an IV injection site; the oedema evoked may cause ischaemic necrosis, necessitating amputation
Warfarin and phenytoin drug interaction with possible purple glove syndrome
WebJan 15, 2024 · “Purple Glove syndrome” is a rare side effect that can occur with intravenous administration of phenytoin. It is characterized by worsening distal limb edema and discoloration which can lead to extensive skin necrosis and limb ischemia. WebOct 9, 2024 · Phenytoin may cause purple glove syndrome. Tell your doctor right away if you or your child have skin discoloration, pain, or swelling at the injection site after receiving phenytoin. Phenytoin may affect blood sugar levels. If you or your child notice a change in the results of your blood or urine sugar tests or if you have any questions ... promise rose houston
Phenytoin Toxicity - StatPearls - NCBI Bookshelf
WebSep 1, 2024 · Purple glove syndrome (PGS) is an atypical adverse drug reaction that can occur after the administration of intravenous phenytoin. Although definitions of PGS vary, it has been loosely defined as signs and symptoms of progressive edema, discoloration, and pain that occurs following administration of intravenous phenytoin [1]. http://patientsafety.pa.gov/ADVISORIES/Pages/200612_12.aspx WebJan 1, 2024 · Purple Glove Syndrome (PGS) is a rare complication of intravenous phenytoin administration which is illustrated by delayed soft tissue injury of the skin conterminous to the point or distal... labor shortage graph 2021