Identification of key genes
WebPPI network analysis of ferroptosis-related DEGs and key ferroptosis-related gene identification. To screen and identify the key genes, we uploaded the ferroptosis-related DEGs to STRING for further analysis, resulting in 31 nodes plus 51 edges. After hiding … WebThe identified key genes, such as TOP2A, ESR1, and KMO, have been demonstrated to be key biomarkers of the liver cancer in many publications. All the results suggest that our method can effectively identify key genes of the liver cancer. Moreover, our method can be applied to other types of data sets to select key genes of other complex diseases.
Identification of key genes
Did you know?
WebWe first identified the key genes and pathways involved in DPN and then analyzed the key genes and pathways involved in both DM and PC. Interestingly, we identified MMP9 as the common hub gene of DM, DPN and PC. The analysis results will provide meaningful clues for the treatment of DM, DPN and PC. Materials and Methods Web8 feb. 2024 · Oral squamous cell carcinoma (OSCC) is one of the most malignant diseases in the world, and the driver genes or signaling pathways remain unclear. This research integrated three OSCC microarray cohorts to screen the key candidate genes positively associated with OSCC progression. Differentially expressed genes (DEGs) were …
Web23 okt. 2024 · The present bioinformatic analysis identified key genes and molecular pathways possibly involved in the metastatic process of UM. A total of 213 DEGs and 14 … Web18 okt. 2024 · Survival analysis identified three key genes, CEACAM5, CEACAM6 and CLCA4, that were closely related to HNSCC prognosis. The Oncomine database, …
Web13 apr. 2024 · Further, through combining the protein–protein interaction networks of the DEGs, it was found that the top five hub genes, namely, ACAN, SFRP2, SFRP4, WNT3, and WNT7B, were also associated with horn development. Our results suggest that only a few key genes, including RXFP2, are involved in bud formation. Web23 sep. 2024 · In this study, Switch Miner software was used to identify key switch genes in the brain whose expression may lead to the development of Alzheimer’s disease. The …
Web16 sep. 2024 · 5. Conclusion. In summary, in this study, based on bioinformatics analysis, we have identified 7 key genes, namely AURKA, CCNA2, CCNB1, CDK1, CKS2, DLGAP5, and MAD2L1 from hundreds of genes and the momentous signaling pathways. AURKA, CCNB1, and CCNA2 are significantly related to the overall survival of CRC patients.
Web16 apr. 2024 · However, in order to identify potential biomarkers associated with AMI, further studies with larger sample sizes are still warranted. 5 Conclusion. In conclusion, … mike tyson organizationWebAnd 16 hub genes (C3AR1, CCR1, CCR2, CD33, CD53, CXCL10, CXCL8, CXCR4, CYBB, FCER1G, FPR2, ITGAL, ITGAM, ITGAX, ITGB2, and LILRB2) were upregulated in carotid atherosclerosis tissue compared with control samples ( Figure 5F ). Figure 5 The selection and analysis of hub genes. mike tyson pay per view costWeb6 jun. 2024 · Thus, the aim of this study was to identify key biomarkers and novel therapeutic targets in thyroid cancer. The expression profiles of GSE3467, GSE5364, … mike tyson overall win loss record