Cisplatin electrolyte

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August undefined, 2024

WebSep 26, 2024 · While generally mild electrolyte deficiencies are pretty benign, moderate/severe abnormalities can cause many life … WebNational Center for Biotechnology Information

(PDF) Incidence and spectrum of electrolyte disturbances …

WebApr 12, 2024 · As previously described, also the cisplatin can induce electrolyte imbalances. In this case, the standard approach to avoid cisplatin-induced nephrotoxicity and the consequent electrolyte alteration is the administration of IV isotonic saline solution in order to stimulate the diuresis. Some authors suggest to add 2 gr of magnesium … WebJul 28, 2024 · Cisplatin is a platinum coordination complex chemotherapy used in the treatment of testicular, ovarian cancer, bladder, and lung cancers, as well as other … dana lynn photography florida

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WebAs cisplatin treatment is clinically associated with diarrhoea and 5-HT is known to be an intestinal secretagogue,16, 17 we investigated the effect of cisplatin on intestinal fluid … WebSep 15, 2024 · Since its approval in 1979 cisplatin has become one of the most extensively used chemotherapeutics in the clinic and although cell resistance and … WebCisplatin is a platinum containing drug first approved as an antineoplastic agent in 1978. It remains an important and effective therapy in many forms of cancer today. … birdsedge first school website

Electrolytes supplementation can decrease the risk of …

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WebAbstract. Cisplatin treatment causes tubulointerstitial injury to the kidneys. Common clinical syndromes associated with its use include acute renal failure and a magnesium wasting … WebMay 24, 2006 · Cisplatin is a well-known nephrotoxic antineoplastic drug. Chronic hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria is one of the … dana lynn photography miami beach flWebDec 16, 2024 · Cisplatin (CDDP; cis-dichlorodiammine platinum [II]) is a non-specific drug of the cell cycle with strong cytotoxicity and broad-spectrum antitumor effects; it is widely used in urogenital system tumors, malignant lymphoma, breast cancer, head and neck cancer, non-small cell lung cancer, etc. ( 1 – 3) Cisplatin-induced nephrotoxicity is … dana lynn bailey workouts

"WebSep 23, 2024 · Background: Cisplatin is an important drug in the treatment of various Cancers. However, this drug causes nephrotoxicity that is linked to electrolyte … " - Cisplatin electrolyte

Cisplatin electrolyte

Electrolyte Disorders Induced by Antineoplastic Drugs

WebJan 12, 2024 · Platinum chemotherapy (Cisplatin), is commonly associated with electrolyte imbalances, including low magnesium (up to 90% using Cisplatin), low potassium, low phosphate, low calcium, and low sodium (up to 43%). This is the type of chemo typically used for lung, colon, ovarian, breast, head/neck, bladder, and testicular cancers. WebCisplatin produces moderate to severe nausea and vomiting in virtually all patients. Nausea and vomiting may start within one hour and may persist for more than 24 hours after chemotherapy. Tolerance may improve with 5-day continuous infusion as compared to rapid, intermittent IV administration.

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WebDrugs & Diseases cisplatin (Rx) Brand and Other Names: Classes: Antineoplastics, Alkylating; Antineoplastics, Platinum Analog Print Dosing & Uses AdultPediatricGeriatric … WebResults: We observed an increase in serum creatinine level to a peak of 1.9 mg/dL (range, 0.8 to 7.8) in the dopamine group, in comparison to 1.4 mg/dL (range, 0.9 to 3.3) in the placebo group (P = .04). Urinary magnesium excretion increased and EGF excretion decreased in both groups.

WebSep 21, 2024 · electrolyte depletion (for example, sodium, potassium). Other important side effects include: jaundice, ringing in the ears ( tinnitus ), sensitivity to light ( photophobia ), rash, pancreatitis, nausea, diarrhea, abdominal pain, and dizziness. Increased blood sugar and uric acid levels also may occur. WebSep 1, 2024 · Cisplatin for injection, USP, a platinum-based drug for intravenous use, is a white to light yellow lyophilized powder. Each vial of Cisplatin for injection, USP …

WebCisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, … WebSep 27, 2024 · Nausea and Vomiting: cisplatin for injection can cause severe nausea and vomiting. Use highly effective antiemetic premedication [see Dosage and Administration ( 2.1) and Warnings and Precautions ( 5.3 )]. • Myelosuppression: cisplatin for injection can cause severe myelosuppression with fatalities due to infections.

WebCisplatin (CP) is a remarkably effective Pt-based anticancer drug, but it also exhibits severe toxic side effects, including nephrotoxicity and ototoxicity, and CP nephrotoxicity is a …

WebMay 24, 2006 · Conclusion: Cisplatin can cause permanent nephrotoxicity, including Gitelman-like syndrome. This drug should be considered among the possible causes of chronic unexplained electrolyte disorders. Publication types Case Reports Review MeSH terms Adult Alkalosis / chemically induced* Antineoplastic Agents / adverse effects* danalynn recer attorneyWebSep 15, 2024 · Since its approval in 1979 cisplatin has become one of the most extensively used chemotherapeutics in the clinic and although cell resistance and toxicity hinder its efficacy it continues to be a gold standard regimen. Cisplatin's side effects primarily include nephrotoxicity, gastrointestinal toxicity, neurotoxicity and ototoxicity. birdsedge first school holidays dan altmann chinatown marketWebJan 1, 2015 · Background: Cisplatin, one of the most commonly used chemotherapeutic agents, has electrolyte imbalances as one of its most important adverse effects. We conducted this study to characterize... dana lynn photography ocean springs msWebMar 1, 2024 · A case of an elderly male presenting with significant recurrent hyponatremia, and prerenal azotemia, with recent exposure to cisplatin along with significant hypovolemia and urinary loss of sodium is reported. Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude … dana lynn photography vimeoWebApr 15, 2024 · Additionally, cisplatin-induced nephrotoxicity led to the unmasking of a familial form of hypomagnesemia. ... Previously, the baseline electrolyte profile was … birdsedge first school hd8 8xrWebJan 3, 2024 · A variety of kidney diseases and electrolyte disorders can result from the drugs that are used to treat malignant disease, including conventional cytotoxic agents; molecularly targeted agents, which take advantage of molecular abnormalities that drive cancer progression; and immunotherapeutic agents. dana machain griswold ct